News archive of selected items
Current and past press releases as well as current and recent short notices
December 12, 2011
Published: Evolution of a detailed physiological model to simulate the gastrointestinal transit and absorption process in humans, Part 2: Extension to describe performance of solid dosage forms.
October 14, 2011
Published: Quantifying stability in gene list ranking across microarray derived clinical biomarkers
October 14, 2011
Published: Evolution of a detailed physiological model to simulate the gastrointestinal transit and absorption process in humans, Part 1: Oral solutions
October 06, 2011
Published Expert Opinion: An update on computational oral absorption simulation
August 01, 2011
Published: PBPK modelling of high- and low-dose etoposide: from adults to children
June 19, 2011
Let’s Make a Model: Opinions and impressions on our work
With its Systems Biology & Computational Solutions global competence center, Bayer Technology Services helps customers better plan their clinical trials ...
May 19, 2011
Prof. Dr. Schuppert of BTS Spokesperson of newly founded Network for mathematical modeling, simulation and optimization
New BMBF based expert committee at the University of Heidelberg
April 29, 2011
Published: Statistical Analysis of Chemical Transformation Kinetics Using Markov-Chain Monte Carlo Methods
April 26, 2011
Published: Evaluation of the Efficacy and Safety of Rivaroxaban Using a Computer Model for Blood Coagulation
April 05, 2011
New compartmental Gastro-Intestinal Model
New GI-Model will be part of PK-Sim 5.0 - get some pre-release information.
March 01, 2011
All new Software Suite with PK-Sim 5 and MoBi 3 due to be released in Summer 2011
Fully redesigned Computational Systems Biology Software Suite
February 08, 2011
Published: A computational systems biology software platform for multiscale modeling and simulation
Integrating whole-body physiology, disease biology, and molecular reaction networks
December 15, 2010
Workshop Announcement for ACoP 2011
Pre- and post-meeting workshops on mechanistic multiscale modeling from whole-body pharmacokinetics and disease biology to molecular reaction networks
September 23, 2010
PK-Sim® Express – Direct integration of gene expression data into PBPK models with PK-Sim®
Computational Systems Biology experts at Bayer Technology Services have developed a new concept for directly integrating tissue specific expression data into physiologically-based pharmacokinetic...
» More
September 07, 2010
Published in MSB: Towards whole-body systems physiology
News and Views Contribution
April 28, 2010
Metabolic engineering review published: Metabolic flux distributions ...
Genetic information, computational predictions, and experimental validation.
December 16, 2009
Physiologically-based Modeling of Therapeutic Proteins is now possible with PK-Sim® Version 4.2!
The recently released PK-Sim® version 4.2 enables scientists in pharmaceutical R&D to simulate the pharmacokinetics of therapeutic proteins in one dynamic model integrating both substance specific...
November 13, 2009
Virtual drug tests increase patient safety: The blood simulator
Digital blood coagulation: scientists from Bayer HealthCare and Bayer Technology Services can investigate the action of drug products even without a laboratory, centrifuges or test tubes. To do this,...
August 27, 2009
Published in CPT: Risk to the Breast-Fed Neonate From Codeine Treatment to the Mother ...
A Quantitative Mechanistic Modeling Study.
April 23, 2009
New on-line services are now available!
New on-line services are now available for users of computational systems biology software solutions and services by Bayer Technology Services (BTS):
The newly created on-line...
February 05, 2009
First milestone reached in research project on the predictive modeling of cancer therapies
Bayer Technology Services and renowned institutions in BMBF FORSYS project
January 30, 2009
PK-Sim® Version 4.1 is now available!
This new version provides many considerable new features that have been requested by our customers and partners. Major improvements are a completely new model structure allowing a better description...
October 10, 2008
Published: Physiology-based simulations of a pathological condition...
...prediction of pharmacokinetics in patients with liver cirrhosis
September 03, 2008
Published in Expert Opinion: Whole body physiologically-based pharmacokinetic models...
...their use in clinical drug development.
July 03, 2008
New poster online: WB-PBPK Population Modeling to Simulate the Influence of Weight and Age...
...on the PK of a combined Oral Contraceptive Containing Drospirenone and Ethinylestradiol
March 01, 2008
Published: General approach for the calculation of tissue to plasma partition coefficients
September 11, 2007
Bayer Technology Services to model the transport of drugs in the liver
Consortium receives funding from the German Federal Ministry of Education and Research
July 05, 2007
LaborPraxis interview with Jörg Lippert
Systembiologie - Modelle für biologische Prozesse
January 15, 2007
Bayer Technology Services Collaborates with the Children’s Hospital of Philadelphia
Pharmacokinetic and Pharmacodynamic Modeling and Simulation Techniques for the Clinic: PK-Sim® Helps to Optimize Drug Therapy for Children
November 24, 2006
Bayer Technology Services at the "Optimizing Drug Development" Conference
From November 29 – December 1, 2006, Bayer Technology Services (BTS) will be presenting its products and services for optimizing drug development at the Congress of the European Federation for...
October 31, 2006
New Tools for the LifeScience Industry – From Systems Biology to Microtechnology
Microtechnology and Systems Biology form a significant basis for research and development performance by enhancing efficiency, reducing capital and human resources required and containing risks by...
October 18, 2005
Simulation of living systems in virtual spaces: Cells growing in the computer
The functions of biological systems are usually attributed to individual biochemical mechanisms. A new discipline known as systems biology, on the other hand, takes a different approach, by...
September 17, 2004
Clinical Response Prediction: New Service from Bayer Technology Services and Physiomics
Bayer Technology Services and the systems biology company Physiomics plc announced a collaborative agreement to cooperate in the field of clinical response prediction.
October 17, 2003
Virtual journey through the body: Software simulates drug absorption
Before a drug reaches its ultimate site of action in the body, it has to overcome a number of obstacles such as passage through the intestinal wall or through the liver. Until recently, the only way...
June 06, 2003
New PK-Sim® Simulation Software
Bayer Technology Services GmbH is offering a new simulation software program. PK-Sim® is the first universally applicable physiology-based pharmacokinetic simulation model.
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