MoBi® Releases

Improvements and enhanced features of MoBi®

What’s new in MoBi® 2.3.6

  1. Bug fixes in population simulation tool.

What’s new in MoBi® 2.1

  1. Processes PBPK-models generated with PK-Sim® 4.1

 

What’s new in MoBi® 2.0.1

  1. Parameters are now specified as functions of other parameters and/or species concentrations
  2. Initial species-concentrations are now specified as functions of parameters and/or initial concentrations of other species
  3. Simulation properties like simulation time, resolution of output time steps, or parameters of the solver are now specified as ordinary parameters and may be used, e.g. in functions or formulas
  4. Derived parameters in PBPK models imported from PK-Sim® are now specified as functions of the corresponding base parameters. Consequently, any derived parameter will be updated automatically if any base parameter like, e.g. lipophilicity, is changed by the user. (The same holds true for the MoBi® toolbox for MATLAB®)
  5. Specification of multiple links in-between compartments is now possible
  6. Access to compound and application data is now possible
  7. Improved and enhanced graphical user interface
  8. Bug fixes

 

What’s new in MoBi® 1.1.2

  1. Enhanced MoBi® toolbox for MATLAB®:
    • Additional optimization algorithm (Simulated Annealing)
    • Additional error function
  1. Minor bug fixes

 

What’s new in MoBi® 1.1.1

First commercially available version of MoBi®

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December 12, 2011

Published: Evolution of a detailed physiological model to simulate the gastrointestinal transit and absorption process in humans, Part 2: Extension to describe performance of solid dosage forms.

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October 20, 2011

Published in Nature: Few inputs can reprogram biological networks

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October 14, 2011

Published: Quantifying stability in gene list ranking across microarray derived clinical biomarkers

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January 25, 2012

33rd EORTC PAMM Winter Meeting (Pharmacology and Molecular Mechanisms Group of the European Organisation for Research and Treatment of Cancer), Jan 25-28, Puerto de la Cruz, Tenerife, Spain

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February 08, 2012

5th International Conference on Advanced Technologies & Treatments for Diabetes (ATTD), February 8-11, Barcelona, Spain

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March 12, 2012

2012 ASCPT Annual Meeting, March 12-17, National Harbor, MD, USA

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