MoBi® Toolbox for R

Integrating Multiscale Physiological Modeling and Simulation with Statistical Computing.

The MoBi® Toolbox for R is a collection of R functions, which allow the processing of models developed in MoBi® from within R.

For example, the R environment can be used to change parameters in a model developed in MoBi®, simulate the model, and analyze the results. This allows an efficient operation in the model analysis stage, using the programming options as well as the libraries available within R in combination with the powerful modeling interface and solver kernel included MoBi®.

The Toolbox includes examples for plotting time courses in dependence of a varying parameter and an identification example, where model parameters are varied to optimize the error between simulation and experimental data.

March 28, 2017

Published in npj Systems Biology and Applications: Translational learning from clinical studies predicts drug pharmacokinetics across patient populations

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December 19, 2016

New publications regarding PBPK modeling: Elderly, Isoniazid, DDI and Diabetes. In addition: A white paper regarding good practices in drug discovery and development

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October 18, 2016

Published in CPT Pharmacometrics & Systems Pharmacology: Applied Concepts in PBPK modeling: How to build a PBPK/PD model

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March 17, 2017

PAGE Meeting 2017, June 06-09, Budapest, Hungary

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October 27, 2016

ACoP Meeting 2016, October 23-26, Seattle, WA, USA

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September 24, 2016

ACCP Annual Meeting 2016, September 25-27, Bethesda, MD, USA

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