PK-Sim® Packages

Modular packages are designed to fit the needs of our customers

PK-Sim^® covers an impressive range of applications that strongly vary in complexity and are geared towards the user needs. The modular design of PK-Sim^® makes it possible to purchase only the desired functions. Thus, the user only pays for the functionality that is desired and avoids the cost for features that will never be used.

Predefined packages are available and are aimed to users in three different R&D stages (click here to view enlarged image of details of the individual PK-Sim® packages):

• PK-Sim^® Research:
  This package is intended for use in the early research and optimization phase. It allows for first predictions of pharmacokinetics from in vitro data as well as the evaluation and interpretation of first in vivo results by modeling the key processes of absorption, distribution, metabolism and excretion ADME. By aiding study design and compound prioritization it helps to increase efficiency in this early stage.

• PK-Sim^® Pre-Clinical:
  With this package the pharmacokinetics of a development candidate can be simulated in great detail in different species. Active processes, such as metabolism and active transport can be modeled in all organs which will lead to an increased understanding of concentration-time curves. This package also contains a PK-PD Module for the integration of activity/toxicity data with organ exposure. PK-Sim^® Pre-Clinical represents an invaluable tool for understanding new compounds and subsequently making the right decisions for development. (download Flyer PK-Sim^® Pre-Clinical)

• PK-Sim^® Clinical:
  This package represents the full version of PK-Sim^®. It contains all of the features included in PK-Sim^® Preclinical plus two additional modules for professional prediction of population kinetics (PK-Pop Module) and estimation of age-dependent clearances (Clearance Scaling Module). This PK-Sim^® package is designed to satisfy the high standards of PK experts involved in clinical development stages. (download Flyer PK-Sim^® Clinical)

Customized bundles of different modules are also possible. If you are interested in a PK-Sim^® package tailored towards your needs, contact us.