Welcome to systems biology and systems pharmacology at Bayer. To support a comprehensive understanding of biological systems, their interaction with pharmaceuticals and the complex dynamic processes involved, Bayer applies mechanistic modeling.

Until recently, Bayer offered software products (Computational Systems Biology Suite including PK-Sim® and MoBi®) and consultancy services for pharmaceutical research and development projects.

The consultancy services have been discontinued following Bayer's new setup as an integrated life sciences company.

The software platform is now developed as an open source project by the Open Systems Pharmacology community. The tools are available under GNU General Public License, version 2.  The latest release can be found here.

We invite everyone in the field of Systems Pharmacology, be it in academia, industry or regulatory bodies, to use the platform. Active participation of computer and modeling & simulation scientists in the further development of the modeling & simulation platform, the incorporated systems models, processes for their qualification and application etc. is encouraged and highly welcome! Please follow the community’s activities at www.open-systems-pharmacology.org.

Open Systems Pharmacology Suite

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April 12, 2017

Two new publications regarding PBPK modeling! : A pregnancy PBPK model has been developed, and evaluated for renally cleared drugs.

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March 28, 2017

Published in npj Systems Biology and Applications: Translational learning from clinical studies predicts drug pharmacokinetics across patient populations

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December 19, 2016

New publications regarding PBPK modeling: Elderly, Isoniazid, DDI and Diabetes. In addition: A white paper regarding good practices in drug discovery and development

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October 14, 2017

ACoP8 Conference, October 15-18 2017 in Florida

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June 25, 2017

14th European ISSX Meeting, June 26-29 2017 in Cologne

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June 05, 2017

PAGE Meeting 2017, June 06-09, Budapest, Hungary

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